Diosmin and hesperidin are two plant flavonoids, close in structure: their formulas differ by 2 hydrogen atoms. What they are used for, Stivits does not claim: the EU register has no authorised health claims for these two ingredients. Hesperidin is found in citrus fruit, and diosmin is isolated from plants or made from hesperidin. The vegan Stivits capsule holds 450 mg of diosmin and 50 mg of hesperidin, 500 mg in total in a ratio of 9:1. Adults take 1 capsule a day with food, and 60 capsules last 60 days. So Stivits names the composition and the dose and does not promise any effect.
| Indicator | Diosmin | Hesperidin |
|---|---|---|
| In 1 Stivits capsule | 450 mg | 50 mg |
| Share of the capsule | 90% | 10% |
| Over 60 days, 60 capsules | 27 g | 3 g |
| Group of flavonoids | Flavone | Flavanone |
| Formula | C28H32O15 | C28H34O15 |
| Molecular mass | 608.5 g/mol | 610.6 g/mol |
| Base of the molecule | Diosmetin | Hesperetin |
| Sugar in the molecule | Rutinose | Rutinose |
| Where it comes from | Isolated from plants or made from hesperidin | Citrus fruit, especially the peel |
The difference between the molecules is small: they have the same sugar, and the formulas differ by 2 hydrogen atoms. That is why diosmin can be made from hesperidin. In the Stivits capsule the two ingredients sit side by side, and their doses are named separately.
Diosmin is a flavonoid from the group of flavones. In structure it is diosmetin bound to the sugar rutinose. It is isolated from various plants or made from hesperidin. The Stivits capsule holds 450 mg of diosmin, which is 90% of the total of the two ingredients.
Hesperidin is a flavonoid from the group of flavanones. It is found in citrus fruit, especially in the peel. In structure it is hesperetin bound to the same rutinose. The Stivits capsule holds 50 mg of hesperidin, which is 10% of the total of the two ingredients.
The Linus Pauling Institute table gives hesperetin, the base of the hesperidin molecule:
| Food, 100 g or 100 ml | Hesperetin |
|---|---|
| Lemon, raw | 27.9 mg |
| Orange, raw | 27.2 mg |
| Lemon juice, fresh | 14.5 mg |
| Orange juice, fresh | 12 mg |
| White grapefruit, raw | Less than 1 mg |
These figures refer to hesperetin, so they cannot be compared directly with the 50 mg of hesperidin in the capsule.
It is a fixed combination: 9 parts of diosmin to 1 part of hesperidin, 500 mg in total. You get both ingredients in 1 capsule a day and do not build the dose from two different products. Over 60 days that is 27 g of diosmin and 3 g of hesperidin.
The downside is clear too. The dose cannot be adjusted, and the capsule holds no other ingredients: no vitamins, no minerals. If you want vitamin C in the same serving, you need a separate product.
The Stivits capsule is a food supplement. In the EU, food supplements are regulated as food, and health claims are taken from the register. The register has no authorised claims for diosmin and hesperidin, so Stivits names the composition and the dose: 450 and 50 mg per capsule.
All three products contain plant flavonoids, but different ones and in different doses.
| Stivits product, daily serving | Flavonoids | Other ingredients | Lasts |
|---|---|---|---|
| Diosmin 450 mg + Hesperidin 50 mg, 1 capsule | Diosmin 450 mg, hesperidin 50 mg | None | 60 days |
| Grape Seed 5000 mg, 1 tablet | Proanthocyanidins 190 mg | None | 90 days |
| Vitamin C 1000 mg+Citrus Bioflavonoids+Rosehip, 1 tablet | Citrus bioflavonoids 25 mg | Vitamin C 1000 mg, rosehip powder 25 mg | 90 days |
Choose the 450 + 50 mg capsule if you are looking for exactly these two ingredients and the exact dose of each. Choose grape seed if you want proanthocyanidins. Choose vitamin C with bioflavonoids if vitamin C matters most to you. The downside of this option: the 25 mg of citrus bioflavonoids may contain hesperidin, but its dose is not named separately.
The capsule suits adults who want exactly diosmin and hesperidin at 450 and 50 mg.
It is not for those who want a combination with vitamins and minerals: the capsule holds none. If you take medicines, are under a doctor's care, are pregnant or breastfeeding, consult a doctor before use.
Adults: 1 capsule a day with food. Do not exceed the recommended daily dose. Store in the original packaging in a dry place at room temperature. Keep out of the reach of young children. Food supplements should not be used as a substitute for a varied and balanced diet.
The EU register has no authorised health claims for diosmin and hesperidin, so Stivits does not say what they are used for and does not promise any effect. We name the composition: 1 vegan Stivits capsule holds 450 mg of diosmin and 50 mg of hesperidin, and 60 capsules last 60 days.
They are two plant flavonoids. Hesperidin is found in citrus fruit, and diosmin is isolated from plants or made from hesperidin. The vegan Stivits capsule holds 450 mg of diosmin and 50 mg of hesperidin.
Diosmin belongs to the flavones, hesperidin to the flavanones. The formulas differ by 2 hydrogen atoms: C28H32O15 and C28H34O15, and the sugar in the molecule is the same. In the Stivits capsule their shares are 90% and 10%.
1 Stivits capsule holds 450 mg of diosmin and 50 mg of hesperidin, 500 mg in total. Adults take 1 capsule a day with food, and 60 capsules last 60 days.
There are 9 parts of diosmin to 1 part of hesperidin. In the Stivits capsule that is 450 and 50 mg. This combination is convenient for anyone who wants both ingredients at once and does not want to build the dose from two products.
No, the EU register has none, so Stivits names only the composition: 450 and 50 mg per capsule. A varied and balanced diet and a healthy lifestyle are important.
Adults take 1 Stivits capsule a day with food. The capsule holds 450 mg of diosmin and 50 mg of hesperidin, and 60 capsules last 60 days. Do not exceed the recommended daily dose.
Stivits does not describe a mechanism or an effect: diosmin and hesperidin have no authorised EU claims. What you can check in the numbers: they are two flavonoids, 450 and 50 mg in 1 Stivits capsule, ratio 9:1.
Stivits does not name or promise a time to a result. We name the time of intake: 1 capsule a day, 60 Stivits capsules in the pack, which is 60 days.
The Stivits instructions do not set the length of a course: 1 capsule a day, and 60 capsules last 60 days. If you plan to take the capsule for longer, especially if you are under a doctor's care or take medicines, discuss it with a doctor first.
If you take medicines, are under a doctor's care, are pregnant or breastfeeding, consult a doctor before use and show them the composition: 450 mg of diosmin and 50 mg of hesperidin in a Stivits capsule.
The Stivits capsule is vegan, without gelatine. Inside are 450 mg of diosmin and 50 mg of hesperidin.
Stivits is a brand of the Estonian company HYPERPHARM OÜ (Tallinn). The supplements are made in Europe, in the EU, in a factory certified to GMP, HACCP and ISO 22000:2018. Stivits sells direct from the factory, with no wholesalers or pharmacies in between.
Stivits sells direct from the factory, with no wholesalers or pharmacies in between. ISO 22000:2018 and GMP confirm the production. We dispatch your order by the next working day. The Stivits shop is rated 4.9 out of 5 on Judge.me, based on 944 reviews. Data updated 6 November 2026.
The composition and doses of the products are taken from the Stivits catalogue, data as of 6 November 2026.